Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PAM | P19021 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568067 | 1.00 | PTGER4 (0.45) | PTGER4PTGER3PTGER2MCL1MAPK1 | |
| SCHEMBL9567941 | 0.81 | MCL1 (0.46) | MCL1MAPK1KDM4EALDH1A1KMT2A | |
| SCHEMBL4272799 | 0.72 | MCL1 (0.51) | MCL1MAPK1KDM4EALDH1A1RXFP1 | |
| SCHEMBL6547490 | 0.70 | PTGER4 (0.50) | PTGER4PTGER3PTGER2PAMKDM4E | |
| SCHEMBL15619314 | 0.69 | MCL1 (0.71) | MCL1MAPK1KDM4EALDH1A1MAPT | |
| SCHEMBL2910452 | 0.69 | ALDH1A1 (0.52) | MCL1MAPK1KDM4EALDH1A1MAPT | |
| SCHEMBL9567940 | 0.69 | MCL1 (0.49) | MCL1MAPK1KDM4EALDH1A1RXFP1 | |
| SCHEMBL29004700 | 0.69 | PTGER4 (0.59) | PTGER4PTGER3PTGER2PAMKDM4E | |
| SCHEMBL27834112 | 0.69 | ALDH1A1 (0.48) | PTGER4PTGER3PTGER2PAMKDM4E | |
| SCHEMBL3248765 | 0.69 | PTGER4 (0.59) | PTGER4PTGER3PTGER2PAMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0568289-A2 | Benzothiophenes and thienothiophenes and related compounds useful, for example, as urokinase inhibitors | Eisai Co., Ltd. (JP) | 1993-11-03 | — | — | EP | disclosed |