Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 6/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4272799 | 0.83 | MCL1 (0.51) | MCL1MAPK1GPR35RXFP1PKM | |
| SCHEMBL15619314 | 0.80 | MCL1 (0.71) | MCL1MAPK1GPR35RXFP1PKM | |
| SCHEMBL2910452 | 0.80 | ALDH1A1 (0.52) | MCL1MAPK1GPR35RXFP1PKM | |
| SCHEMBL4860970 | 0.80 | MCL1 (0.45) | MCL1MAPK1GPR35HPGDKDM4E | |
| SCHEMBL26049804 | 0.78 | EDNRA (0.50) | MCL1MAPK1GPR35RXFP1PKM | |
| SCHEMBL9567941 | 0.78 | MCL1 (0.46) | MCL1MAPK1GPR35RXFP1PKM | |
| SCHEMBL2889156 | 0.75 | TSHR (0.53) | MCL1MAPK1GPR35RXFP1PKM | |
| SCHEMBL9025199 | 0.74 | STING1 (0.54) | MCL1MAPK1HPGDLMNAKDM4E | |
| SCHEMBL24857843 | 0.72 | IDO1 (0.36) | MAPK1HPGDKDM4EALDH1A1GLA | |
| SCHEMBL584871 | 0.72 | RXFP1 (0.71) | MCL1MAPK1GPR35RXFP1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0568289-A2 | Benzothiophenes and thienothiophenes and related compounds useful, for example, as urokinase inhibitors | Eisai Co., Ltd. (JP) | 1993-11-03 | — | — | EP | disclosed |