Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 2/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 11/20 | 0.45 |
| ▸ | F2 | P00734 | 10/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 8/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 8/20 | 0.45 |
| ▸ | PLG | P00747 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568078 | 1.00 | SCN1A (0.46) | SCN1ASCN2ASCN3AST14F2 | |
| SCHEMBL9568246 | 0.87 | F2 (0.41) | SCN1ASCN2ASCN3AST14F2 | |
| SCHEMBL9568245 | 0.87 | F2 (0.41) | SCN1ASCN2ASCN3AST14F2 | |
| SCHEMBL9568208 | 0.87 | SCN1A (0.44) | SCN1ASCN2ASCN3AMEN1NPC1 | |
| SCHEMBL9568210 | 0.87 | SCN1A (0.44) | SCN1ASCN2ASCN3AMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL9568149 | 0.84 | MEN1 (0.45) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL9185970 | 0.83 | MEN1 (0.54) | ST14F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL8410586 | 0.82 | MEN1 (0.52) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL9568143 | 0.81 | PRSS1 (0.53) | ST14F2PRSS1PRSS2PRSS3 | |
| SCHEMBL9568138 | 0.81 | PRSS1 (0.53) | ST14F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |