Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 4/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.53 |
| ▸ | PLG | P00747 | 3/20 | 0.53 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.53 |
| ▸ | F2 | P00734 | 3/20 | 0.53 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.53 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.42 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568143 | 1.00 | PRSS1 (0.53) | PRSS1PRSS2PRSS3PLGTPSAB1 | |
| SCHEMBL9568212 | 0.89 | SMN1; SMN2 (0.45) | PRSS1PRSS2PRSS3PLGTPSAB1 | |
| SCHEMBL9568207 | 0.89 | SMN1; SMN2 (0.45) | PRSS1PRSS2PRSS3PLGTPSAB1 | |
| SCHEMBL9568104 | 0.83 | SMN1; SMN2 (0.48) | PRSS1PRSS2PRSS3PLGTPSAB1 | |
| SCHEMBL9568080 | 0.81 | SCN1A (0.46) | PRSS1PRSS2PRSS3PLGTPSAB1 | |
| SCHEMBL9568078 | 0.81 | SCN1A (0.46) | PRSS1PRSS2PRSS3PLGTPSAB1 | |
| SCHEMBL9568226 | 0.77 | F2 (0.53) | PRSS1PRSS2PRSS3PLGTPSAB1 | |
| Hydrochloric Acid SCHEMBL9568149 | 0.76 | MEN1 (0.45) | PRSS1PRSS2PRSS3PLGTPSAB1 | |
| SCHEMBL12879090 | 0.75 | SMN1; SMN2 (0.68) | PRSS1PRSS2PRSS3PLGTPSAB1 | |
| SCHEMBL4197556 | 0.74 | SMN1; SMN2 (0.67) | PRSS1PRSS2PRSS3PLGTPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |