Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 4/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.41 |
| ▸ | BMPR1A | P36894 | 2/20 | 0.41 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568245 | 1.00 | F2 (0.41) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL9568084 | 0.90 | F2 (0.46) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL9568086 | 0.90 | F2 (0.46) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL9568128 | 0.90 | SCN1A (0.38) | BMPR1BBMPR1AACVRL1ACVR1CFTR | |
| SCHEMBL9568132 | 0.90 | SCN1A (0.38) | BMPR1BBMPR1AACVRL1ACVR1CFTR | |
| Hydrochloric Acid SCHEMBL9568183 | 0.90 | F2 (0.46) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL8410171 | 0.87 | CFTR (0.48) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL9568078 | 0.87 | SCN1A (0.46) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL9568080 | 0.87 | SCN1A (0.46) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL8410563 | 0.83 | KDM1A (0.48) | F2ST14PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |