Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 4/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.46 |
| ▸ | PLG | P00747 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568084 | 1.00 | F2 (0.46) | F2ST14PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL9568183 | 0.99 | F2 (0.46) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL9568246 | 0.90 | F2 (0.41) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL9568245 | 0.90 | F2 (0.41) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL8410171 | 0.90 | CFTR (0.48) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL9568234 | 0.89 | ALDH1A1 (0.43) | PDE4APDE4BPDE4CPDE4DKDM1A | |
| SCHEMBL9568196 | 0.87 | F2 (0.44) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL9568200 | 0.87 | F2 (0.44) | F2ST14PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL9568164 | 0.86 | F2 (0.43) | F2ST14PRSS1PRSS2PRSS3 | |
| SCHEMBL8410563 | 0.86 | KDM1A (0.48) | F2ST14PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | claimed |
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |