Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.42 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568031 | 0.81 | MEN1 (0.44) | MEN1KMT2AALDH1A1HTT | |
| SCHEMBL9048669 | 0.79 | MEN1 (0.42) | MEN1KMT2AALDH1A1HTTTSHR | |
| SCHEMBL9567965 | 0.78 | KDM4C (0.48) | MEN1KMT2AEPHX2ALDH1A1HTT | |
| SCHEMBL31613080 | 0.78 | ALDH1A1 (0.52) | ALDH1A1HTTXBP1PTGDR2RAB9A | |
| SCHEMBL29706163 | 0.77 | HTT (0.54) | MEN1KMT2AALDH1A1HTTRAB9A | |
| SCHEMBL2792830 | 0.77 | HTT (0.54) | MEN1KMT2AALDH1A1HTTRAB9A | |
| SCHEMBL29608780 | 0.77 | HTT (0.54) | MEN1KMT2AALDH1A1HTTRAB9A | |
| SCHEMBL29484110 | 0.77 | HTT (0.54) | MEN1KMT2AALDH1A1HTTRAB9A | |
| SCHEMBL2796237 | 0.77 | HTT (0.54) | MEN1KMT2AALDH1A1HTTRAB9A | |
| SCHEMBL242244 | 0.77 | HTT (0.54) | MEN1KMT2AALDH1A1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |