Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.48 |
| ▸ | KDM5A | P29375 | 2/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567967 | 0.87 | TRPV1 (0.44) | KDM4CKDM5AKDM5BEPHX2HTT | |
| SCHEMBL9048031 | 0.82 | MEN1 (0.39) | KDM4CKDM5AKDM5BHTTALDH1A1 | |
| SCHEMBL3590904 | 0.80 | FFAR1 (0.52) | KDM4CKDM5AKDM5BHTTALDH1A1 | |
| SCHEMBL30301824 | 0.80 | FFAR1 (0.52) | KDM4CKDM5AKDM5BHTTALDH1A1 | |
| SCHEMBL9427323 | 0.80 | SIGMAR1 (0.40) | KDM4CHTTALDH1A1MEN1KMT2A | |
| SCHEMBL9568094 | 0.78 | MEN1 (0.49) | EPHX2HTTALDH1A1XBP1MEN1 | |
| SCHEMBL7038866 | 0.77 | HAO1 (0.53) | KDM4CKDM5AKDM5BHTTALDH1A1 | |
| SCHEMBL9427333 | 0.77 | PTGIR (0.58) | KDM4C | |
| SCHEMBL16066912 | 0.77 | ESR1 (0.46) | KDM4CL3MBTL1KDM6B | |
| SCHEMBL1568052 | 0.77 | BLM (0.51) | KDM4CKDM5AKDM5BHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |