Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.45 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.45 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568143 | 0.83 | PRSS1 (0.53) | SMN1; SMN2CYP2C19F2PRSS1TPSAB1 | |
| SCHEMBL9568138 | 0.83 | PRSS1 (0.53) | SMN1; SMN2CYP2C19F2PRSS1TPSAB1 | |
| Hydrochloric Acid SCHEMBL9568096 | 0.77 | MCHR1 (0.37) | GPR119F2PRSS1TPSAB1TPSD1 | |
| SCHEMBL9568226 | 0.75 | F2 (0.53) | SMN1; SMN2CYP2C19GPR119F2PRSS1 | |
| SCHEMBL9568207 | 0.74 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP2C19F2PRSS1TPSAB1 | |
| SCHEMBL9568212 | 0.74 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP2C19F2PRSS1TPSAB1 | |
| SCHEMBL31452936 | 0.74 | SMN1; SMN2 (0.65) | SMN1; SMN2CYP2C19NPC1RAB9AHTT | |
| SCHEMBL12879090 | 0.74 | SMN1; SMN2 (0.68) | SMN1; SMN2CYP2C19F2PRSS1TPSAB1 | |
| Hydrochloric Acid SCHEMBL8887529 | 0.73 | F2 (0.45) | SMN1; SMN2F2PRSS1PLGPRSS2 | |
| SCHEMBL8887118 | 0.73 | USP30 (0.44) | F2PRSS1PRSS2PRSS3USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |