Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL955189 | 0.85 | BRD4 (0.45) | BRD4KCNH2CALM1ALDH1A1HMGCR | |
| SCHEMBL3406550 | 0.79 | KCNH2 (0.41) | BRD4KCNH2CALM1ALDH1A1HMGCR | |
| SCHEMBL3407693 | 0.78 | BRD4 (0.42) | BRD4KCNH2CALM1ALDH1A1HMGCR | |
| Ammonia Solution, Strong SCHEMBL27432333 | 0.77 | BRD4 (0.47) | BRD4KCNH2CALM1ALDH1A1 | |
| SCHEMBL11330543 | 0.77 | KCNH2 (0.62) | BRD4KCNH2CALM1ALDH1A1GAA | |
| SCHEMBL13670084 | 0.75 | BRD4 (0.45) | BRD4KCNH2CALM1ALDH1A1HMGCR | |
| SCHEMBL13670464 | 0.71 | BRD4 (0.42) | BRD4KCNH2CALM1ALDH1A1HMGCR | |
| SCHEMBL25205794 | 0.68 | BRD4 (0.49) | BRD4KCNH2CALM1ALDH1A1GAA | |
| SCHEMBL22576217 | 0.68 | ALDH1A1 (0.55) | BRD4KCNH2CALM1ALDH1A1RAB9A | |
| SCHEMBL3916327 | 0.68 | BRD4 (0.53) | BRD4KCNH2CALM1ALDH1A1FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8617723-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2013-12-31 | — | — | US | disclosed |
| US-20110012100-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110012100-A1 | METAL COMPLEXES | AP1M1, AP3M1, SOD1 | BRD4 2197/4885KCNH2 360/4885CALM1 368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.