Isophthalic Dicarboxaldehyde

Isophthalic Dicarboxaldehyde

SCHEMBL9568121

[2H]C(=O)c1cccc(C=O)c1

nearest known ligand 0.60

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
UNG P13051 1/20 0.48
CYP2A6 P11509 1/20 0.48
SRC P12931 1/20 0.42
TRIM24 O15164 1/20 0.41
TRIM33 Q9UPN9 1/20 0.41
MAOA P21397 7/20 0.41
MAOB P27338 7/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
FGFR1 P11362 1/20 0.40
RAB9A P51151 2/20 0.39
KDM4E B2RXH2 1/20 0.39
PTGS2 P35354 1/20 0.39
BRD4 O60885 1/20 0.37
NPC1 O15118 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isophthalic Dicarboxaldehyde SCHEMBL13992161 0.92 ALDH1A1 (0.48) ALDH1A1UNGCYP2A6SRCTRIM24
Isophthalic Dicarboxaldehyde SCHEMBL180566 0.87 ALDH1A1 (0.67) ALDH1A1UNGCYP2A6SRCTRIM24
Isophthalic Dicarboxaldehyde SCHEMBL4952540 0.87 ALDH1A1 (0.67) ALDH1A1UNGCYP2A6SRCTRIM24
Isophthalic Dicarboxaldehyde SCHEMBL28611144 0.84 ALDH1A1 (0.67) ALDH1A1UNGCYP2A6SRCTRIM24
Isophthalic Dicarboxaldehyde SCHEMBL20477528 0.81 ALDH1A1 (0.61) ALDH1A1UNGCYP2A6SRCTRIM24
Isophthalic Dicarboxaldehyde SCHEMBL4304012 0.81 ALDH1A1 (0.63) ALDH1A1UNGCYP2A6SRCTRIM24
Isophthalic Dicarboxaldehyde SCHEMBL16267528 0.79 ALDH1A1 (0.58) ALDH1A1UNGCYP2A6SRCTRIM24
Isophthalic Dicarboxaldehyde SCHEMBL8543662 0.78 ALDH1A1 (0.46) ALDH1A1UNGCYP2A6SRCTRIM24
SCHEMBL149900 0.75 ALDH1A1 (0.54) ALDH1A1UNGCYP2A6SRCTRIM24
SCHEMBL6521692 0.75 ALDH1A1 (0.54) ALDH1A1UNGCYP2A6SRCTRIM24

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0552881-A1 Anticancer benzaldehyde compounds NORSK HYDRO A/S (NO) 1993-07-28 EP disclosed