Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.44 |
| ▸ | F2 | P00734 | 5/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.44 |
| ▸ | TPSD1 | Q9BZJ3 | 4/20 | 0.44 |
| ▸ | TPSG1 | Q9NRR2 | 4/20 | 0.44 |
| ▸ | PLG | P00747 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422701 | 0.87 | ITGB3 (0.52) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| SCHEMBL9568110 | 0.87 | ITGB3 (0.52) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| SCHEMBL9568111 | 0.86 | ITGB3 (0.45) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| Hydrochloric Acid SCHEMBL9568112 | 0.86 | ITGB3 (0.52) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| Hydrochloric Acid SCHEMBL9568150 | 0.86 | ITGB3 (0.52) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| Hydrochloric Acid SCHEMBL9568100 | 0.86 | ITGB3 (0.52) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| SCHEMBL9568120 | 0.86 | PRSS1 (0.53) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| Hydrochloric Acid SCHEMBL9568167 | 0.85 | ITGB3 (0.44) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| Hydrochloric Acid SCHEMBL9568180 | 0.85 | PRSS1 (0.52) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| SCHEMBL9568134 | 0.83 | YAP1 (0.39) | ITGB3ITGA2BHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |