Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568449 | 0.92 | PRKCZ (0.38) | PRKCZMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9568390 | 0.91 | PRKCZ (0.35) | PRKCZMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9568299 | 0.90 | MAPT (0.40) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9568432 | 0.90 | TOP1 (0.39) | TOP1NEK1 | |
| SCHEMBL9568351 | 0.84 | PRKCZ (0.37) | PRKCZTOP1MAPTMEN1KMT2A | |
| SCHEMBL9568386 | 0.82 | PRKCZ (0.39) | PRKCZMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9568298 | 0.81 | LMNA (0.39) | PRKCZMEN1KMT2AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9568570 | 0.80 | LMNA (0.36) | TOP1ALDH1A1TDP1 | |
| SCHEMBL9568400 | 0.80 | LMNA (0.37) | TOP1ALDH1A1HPGDTDP1ALOX15 | |
| SCHEMBL9568366 | 0.80 | MAPT (0.40) | MAPTMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551518-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-07-21 | — | — | EP | disclosed |