Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.62 |
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9659527 | 1.00 | MEN1 (0.62) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL95686 | 1.00 | MEN1 (0.62) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL9076121 | 0.99 | MEN1 (0.65) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL10538827 | 0.86 | MAPT (0.63) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL1143128 | 0.86 | MAPT (0.59) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL8645013 | 0.86 | MAPT (0.63) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL8645016 | 0.86 | MAPT (0.63) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL1143127 | 0.86 | MAPT (0.59) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL9076641 | 0.86 | MAPT (0.59) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL4837027 | 0.85 | MEN1 (0.47) | MEN1KMT2AMAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555769-B1 | Process for the preparation of Cephem-Prodrug-esters | HOECHST AG (DE) | 1999-09-15 | — | — | EP | claimed |
| US-4988816-A | Chemical intermediates for cephalosporin antibiotics | ROUSSEL UCLAF (FR) | 1991-01-29 | — | — | US | claimed |
| JP-7173140-A | — | — | None | — | — | JP | disclosed |
| JP-7082253-A | — | — | None | — | — | JP | disclosed |
| JP-7179445-A | — | — | None | — | — | JP | disclosed |
| WO-2026107208-A1 | COMPOSITIONS AND METHODS FOR TREATING MICROBIAL INFECTIONS | THE METHODIST HOSPITAL (US) | 2026-05-21 | — | — | WO | disclosed |
| US-20230227444-A1 | BETA-LACTAM COMPOUND, USE THEREOF AND PREPARATION METHOD THEREFOR | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2023-07-20 | — | — | US | disclosed |
| US-20230227444-A1 | BETA-LACTAM COMPOUND, USE THEREOF AND PREPARATION METHOD THEREFOR | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2023-07-20 | — | — | US | disclosed |
| US-20230114728-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | VenatoRx Pharmaceuticals, Inc. | 2023-04-13 | — | — | US | disclosed |
| US-11332485-B2 | Penicillin-binding protein inhibitors | VenatoRx Pharmaceuticals, Inc. (US) | 2022-05-17 | — | — | US | disclosed |
| US-11332485-B2 | Penicillin-binding protein inhibitors | VenatoRx Pharmaceuticals, Inc. (US) | 2022-05-17 | — | — | US | disclosed |
| US-4487937-A | CEPHALOSPORIN INTERMETIATE | ROUSSEL UCLAF (FR) | 1984-12-11 | — | — | US | disclosed |
| US-4483981-A | ANTIBIOTICS, BACTERICIDES | ROUSSEL UCLAF (FR) | 1984-11-20 | — | — | US | disclosed |
| US-4386210-A | CEPHALOSPORIN ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1983-05-31 | — | — | US | disclosed |
| US-4376203-A | ANTIBIOTIC | ROUSSELL UCLAF (FR) | 1983-03-08 | — | — | US | disclosed |
| US-4288434-A | Cephalosporanic acid derivatives | ROUSSEL UCLAF (FR) | 1981-09-08 | — | — | US | disclosed |
| US-4283396-A | 3-Acetoxymethyl-7-(hydroxyiminoacetamido)-cephalosporanic acid derivatives | ROUSSEL UCLAF (FR) | 1981-08-11 | — | — | US | disclosed |
| US-4278671-A | ANTIBIOTICS, BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-07-14 | — | — | US | disclosed |
| US-4196205-A | ANTIBIOTICS, BACTERICIDES | ROUSSEL UCLAF (FR) | 1980-04-01 | — | — | US | disclosed |
| US-4152432-A | ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1979-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227444-A1 | BETA-LACTAM COMPOUND, USE THEREOF AND PREPARATION METHOD THEREFOR | COASY, CYP51A1, DCXR | MEN1 1182/4885KMT2A 4259/4885MAPT 4462/4885 |
| US-20230114728-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | PEPD, BPGM, EBPL | MEN1 3629/4885KMT2A 2536/4885MAPT 3146/4885 |
| US-11332485-B2 | Penicillin-binding protein inhibitors | PEPD, BPGM, EBPL | MEN1 3629/4885KMT2A 2536/4885MAPT 3146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.