Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13916941 | 0.92 | MAPT (0.50) | ABCG2KMT2AMAPTMEN1LMNA | |
| SCHEMBL6055977 | 0.92 | MAPT (0.50) | ABCG2KMT2AMAPTMEN1LMNA | |
| SCHEMBL6055975 | 0.92 | MAPT (0.50) | ABCG2KMT2AMAPTMEN1LMNA | |
| SCHEMBL11242541 | 0.88 | GSK3B (0.49) | ABCG2KMT2AMAPTMEN1LMNA | |
| Anisaldehyde SCHEMBL7613578 | 0.87 | ALDH1A1 (0.54) | ABCG2KMT2AMAPTMEN1LMNA | |
| SCHEMBL5617195 | 0.86 | ABCG2 (0.54) | ABCG2KMT2AMAPTMEN1LMNA | |
| SCHEMBL5617197 | 0.86 | ABCG2 (0.54) | ABCG2KMT2AMAPTMEN1LMNA | |
| SCHEMBL9568614 | 0.85 | ABCG2 (0.56) | ABCG2MAPTNPSR1CYP1A2GSK3B | |
| SCHEMBL18704227 | 0.85 | ABCG2 (0.56) | ABCG2MAPTNPSR1CYP1A2GSK3B | |
| SCHEMBL3952982 | 0.84 | MAPT (0.49) | KMT2AMAPTMEN1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2324863-B1 | Method for producing artificial skin | SHISEIDO CO LTD (JP) | 2013-07-31 | — | — | EP | disclosed |
| EP-2324863-A1 | Method for producing artificial skin | SHISEIDO COMPANY, LTD. (JP) | 2011-05-25 | — | — | EP | disclosed |
| US-7927634-B2 | Compositions and methods for treating angiogenesis-related diseases, wounds and cosmetic use of components of Angelica sinensis, and methods of preparation thereof | SUNNY BIODISCOVERY, INC. (US) | 2011-04-19 | — | — | US | disclosed |
| US-20100255069-A1 | COMPOSITIONS AND METHODS FOR TREATING ANGIOGENESIS-RELATED DISEASES, WOUNDS AND COSMETIC USE OF COMPONENTS OF ANGELICA SINENSIS, AND METHODS OF PREPARATION THEREOF | SUNNY BIODISCOVERY, INC. (US) | 2010-10-07 | — | — | US | disclosed |
| US-7645595-B2 | Method of production of artificial skin | SHISEIDO COMPANY, LTD. (JP) | 2010-01-12 | — | — | US | disclosed |
| US-20080248571-A1 | Method of Production of Artificial Skin | SHISEIDO COMPANY, LTD. (JP) | 2008-10-09 | — | — | US | disclosed |
| US-20080241101-A1 | Skin vitalizing composition for external use anti-aging preparation | SHISEIDO COMPANY, LTD. | 2008-10-02 | — | — | US | disclosed |
| EP-1066816-B1 | AGENTS PROMOTING LAMININ PRODUCTION IN SKIN CELLS | SHISEIDO CO LTD (JP) | 2007-08-01 | — | — | EP | disclosed |
| US-20060159782-A1 | Material for promoting skin basement formation | SHISEIDO COMPANY, LTD. (JP) | 2006-07-20 | — | — | US | disclosed |
| US-20060068032-A1 | Compositions and methods for treating angiogenesis-related diseases, wounds and cosmetic use of components of Angelica sinensis, and methods of preparation thereof | SUNNY BIODISCOVERY, INC. (US) | 2006-03-30 | — | — | US | disclosed |
| US-20020168425-A1 | COLLAGEN PRODUCTION PROMOTER COMPOSITION | NAKAYAMA YASUKAZU (JP) | 2002-11-14 | — | — | US | disclosed |
| EP-1180371-A1 | AGENTS PROMOTING THE FORMATION OF SKIN BASEMENT MEMBRANE, AGENTS PROMOTING THE FORMATION OF ARTIFICIAL SKIN AND PROCESS FOR PRODUCING ARTIFICIAL SKIN | SHISEIDO COMPANY LIMITED (JP) | 2002-02-20 | — | — | EP | disclosed |
| EP-0688559-B1 | Skin anti-ageing composition | SHISEIDO CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| EP-1066816-A1 | AGENTS PROMOTING LAMININ PRODUCTION IN SKIN CELLS | SHISEIDO COMPANY LIMITED (JP) | 2001-01-10 | — | — | EP | disclosed |
| US-6077520-A | ANTI-AGING TOPICAL COMPOSITION INCLUDING AT LEAST ONE OF SULFONYLETHYLENEAMINE OR MERCAPTOSULFONYLETHYLENEAMINE COMPOUNDS OF GIVEN FORMULA AND SPECIFIED ULTRAVIOLET LIGHT PROTECTIVE AGENTS | SHISEIDO COMPANY, LTD. (JP) | 2000-06-20 | — | — | US | disclosed |
| EP-0900561-A1 | COMPOSITIONS PROMOTING COLLAGEN PRODUCTION | SHISEIDO COMPANY LIMITED (JP) | 1999-03-10 | — | — | EP | disclosed |
| US-5853705-A | Anti-aging cosmetic composition | SHISEIDO COMPANY, LTD. (JP) | 1998-12-29 | — | — | US | disclosed |
| US-5747049-A | AMINOETHYLSULFINIC ACID OR AMINOETHYLTHIOSULFONIC ACID, SUNSCREEN | SHISEIDO COMPANY, LTD. (JP) | 1998-05-05 | — | — | US | disclosed |
| EP-0797984-A2 | Anti-aging cosmetic composition | SHISEIDO COMPANY LIMITED (JP) | 1997-10-01 | — | — | EP | disclosed |
| EP-0688559-A1 | Skin anti-ageing composition | SHISEIDO COMPANY LIMITED (JP) | 1995-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080241101-A1 | Skin vitalizing composition for external use anti-aging preparation | MMP15, MMP14, SERPINE1 | ABCG2 3155/4885KMT2A 3166/4885MAPT 2217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.