SCHEMBL9568638

SCHEMBL9568638

C=CC(=O)Nc1ccc(NS(C)(=O)=O)cc1

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 12/20 0.70
F13A1 P00488 3/20 0.58
TGM1 P22735 3/20 0.58
LMNA P02545 3/20 0.58
TGM3 Q08188 1/20 0.58
KDM4E B2RXH2 2/20 0.49
THRA P10827 1/20 0.49
THRB P10828 1/20 0.49
GSTO1 P78417 1/20 0.48
XDH P47989 1/20 0.48
ALDH1A1 P00352 1/20 0.47
HPGD P15428 1/20 0.47
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
KEAP1 Q14145 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27806115 0.84 TGM2 (0.62) TGM2F13A1TGM1LMNATGM3
SCHEMBL9568629 0.83 TGM2 (0.58) TGM2KDM4EGSTO1ALDH1A1HPGD
SCHEMBL9568569 0.83 HPGD (0.65) TGM2F13A1TGM1LMNATGM3
SCHEMBL439369 0.82 TGM2 (0.79) TGM2F13A1TGM1LMNATGM3
SCHEMBL10405297 0.82 TGM2 (1.00) TGM2F13A1TGM1LMNATGM3
SCHEMBL27403592 0.80 TGM2 (0.71) TGM2F13A1TGM1LMNATGM3
SCHEMBL21247525 0.80 TGM2 (0.81) TGM2F13A1TGM1LMNATGM3
SCHEMBL395544 0.79 TGM2 (0.58) TGM2LMNAKDM4EALDH1A1HPGD
SCHEMBL31233334 0.79 HPGD (0.53) TGM2LMNAKDM4ETHRBALDH1A1
SCHEMBL27632063 0.78 TGM2 (0.64) TGM2F13A1TGM1LMNATGM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed