SCHEMBL9568569

SCHEMBL9568569

C=CC(=O)Nc1ccc(NS(=O)(=O)CC)cc1

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.65
TGM2 P21980 12/20 0.61
LMNA P02545 3/20 0.54
F13A1 P00488 3/20 0.54
TGM1 P22735 3/20 0.54
TGM3 Q08188 1/20 0.54
THRA P10827 1/20 0.54
THRB P10828 1/20 0.54
HTT P42858 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
GSTO1 P78417 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568667 0.84 TGM2 (0.55) HPGDTGM2LMNAGSTO1
SCHEMBL9568638 0.83 TGM2 (0.70) HPGDTGM2LMNAF13A1TGM1
SCHEMBL395814 0.81 TGM2 (0.56) HPGDTGM2LMNATHRATHRB
SCHEMBL27806115 0.81 TGM2 (0.62) TGM2LMNAF13A1TGM1TGM3
SCHEMBL439369 0.80 TGM2 (0.79) TGM2LMNAF13A1TGM1TGM3
SCHEMBL21104559 0.79 HPGD (1.00) HPGDLMNAHTTSMN1; SMN2
SCHEMBL9568488 0.78 HPGD (0.54) HPGDTGM2LMNATHRBHTT
SCHEMBL9568784 0.78 PSIP1 (0.50) HPGDTGM2LMNA
SCHEMBL1132464 0.77 THRA (0.67) TGM2LMNAF13A1TGM1TGM3
SCHEMBL398579 0.77 HPGD (0.70) HPGDLMNAHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed