SCHEMBL9568661

SCHEMBL9568661

C=CC(=O)Nc1cccc(S(=O)(=O)NC(C)C)c1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
HTR2B P41595 1/20 0.52
TGM2 P21980 6/20 0.51
CA1 P00915 4/20 0.48
CA2 P00918 4/20 0.48
CA12 O43570 3/20 0.48
CA9 Q16790 3/20 0.48
KIF18A Q8NI77 1/20 0.46
HDAC8 Q9BY41 2/20 0.44
HDAC6 Q9UBN7 2/20 0.44
F13A1 P00488 2/20 0.44
TGM1 P22735 2/20 0.44
TGM3 Q08188 1/20 0.44
PKM P14618 1/20 0.42
GSTO1 P78417 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568603 0.87 CA1 (0.52) LMNASMN1; SMN2TGM2CA1CA2
SCHEMBL9568763 0.85 TGM2 (0.55) LMNASMN1; SMN2TGM2CA1CA2
SCHEMBL9568781 0.83 TGM2 (0.48) LMNASMN1; SMN2TGM2CA1CA2
SCHEMBL9568652 0.83 TGM2 (0.65) LMNATGM2F13A1TGM1TGM3
SCHEMBL27404069 0.82 TGM2 (0.52) LMNASMN1; SMN2TGM2CA1CA2
SCHEMBL30595307 0.81 TGM2 (0.67) LMNASMN1; SMN2TGM2F13A1TGM1
SCHEMBL398959 0.81 TDP1 (0.55) LMNASMN1; SMN2HTR2BCA1CA2
SCHEMBL9568617 0.81 KDM4E (0.54) LMNASMN1; SMN2TGM2KIF18AF13A1
SCHEMBL9568715 0.81 TGM2 (0.51) LMNASMN1; SMN2TGM2CA1CA2
SCHEMBL9568796 0.81 TGM2 (0.58) LMNATGM2HDAC8HDAC6F13A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed