SCHEMBL9568617

SCHEMBL9568617

C=CC(=O)Nc1cccc(S(=O)(=O)NC(C)(C)C)c1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.54
MEN1 O00255 1/20 0.54
NPC1 O15118 1/20 0.54
LMNA P02545 1/20 0.54
MAPT P10636 1/20 0.54
HPGD P15428 1/20 0.54
RAB9A P51151 1/20 0.54
KMT2A Q03164 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
TGM2 P21980 4/20 0.51
KIF18A Q8NI77 13/20 0.46
GSTO1 P78417 1/20 0.45
F13A1 P00488 1/20 0.44
TGM1 P22735 1/20 0.44
TGM3 Q08188 1/20 0.44
ACKR3 P25106 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568763 0.85 TGM2 (0.55) MEN1LMNAMAPTHPGDRAB9A
SCHEMBL27404069 0.82 TGM2 (0.52) MEN1LMNAMAPTHPGDKMT2A
SCHEMBL30595307 0.81 TGM2 (0.67) MEN1LMNAKMT2ASMN1; SMN2TGM2
SCHEMBL9568661 0.81 LMNA (0.52) LMNASMN1; SMN2TGM2KIF18AGSTO1
SCHEMBL397299 0.81 TDP1 (0.55) KDM4EMEN1NPC1LMNAMAPT
SCHEMBL9568715 0.81 TGM2 (0.51) MEN1LMNAMAPTKMT2ASMN1; SMN2
SCHEMBL9568796 0.81 TGM2 (0.58) MEN1LMNAMAPTHPGDKMT2A
SCHEMBL1813367 0.80 TGM2 (0.59) LMNAMAPTSMN1; SMN2TGM2GSTO1
SCHEMBL9568485 0.79 ALDH1A1 (0.50) LMNAKMT2ASMN1; SMN2TGM2F13A1
SCHEMBL27403961 0.79 TGM2 (0.49) MEN1LMNAMAPTHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed