Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.50 |
| ▸ | MAOA | P21397 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.45 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540720 | 0.76 | F2 (0.57) | MAOBMAOANPC1RAB9AMAPT | |
| SCHEMBL8854243 | 0.75 | ABCC9 (0.40) | RAB9AMAPT | |
| SCHEMBL4526884 | 0.73 | MAOB (0.65) | MAOBMAOANPC1RAB9AMAPT | |
| SCHEMBL22803696 | 0.73 | NPC1 (0.67) | MAOBMAOANPC1RAB9AMAPT | |
| SCHEMBL16351333 | 0.72 | MAOB (0.49) | MAOBMAOANPC1RAB9AMAPT | |
| SCHEMBL22803844 | 0.71 | ESR1 (0.61) | MAOBMAOANPC1RAB9AMAPT | |
| SCHEMBL31668688 | 0.71 | MAOA (0.66) | MAOBMAOANPC1RAB9AMAPT | |
| SCHEMBL4347943 | 0.71 | NPC1 (0.69) | MAOBMAOANPC1RAB9AMAPT | |
| SCHEMBL31668680 | 0.71 | MAOB (0.88) | MAOBMAOANPC1RAB9AMAPT | |
| SCHEMBL5177372 | 0.70 | MAOB (0.83) | MAOBMAOANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542497-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |