SCHEMBL9568836

SCHEMBL9568836

C=CC(=O)NCCNS(=O)(=O)c1cccc2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPY5R Q15761 2/20 0.54
SCN1A P35498 2/20 0.53
SCN2A Q99250 2/20 0.53
SCN3A Q9NY46 2/20 0.53
CYP3A4 P08684 2/20 0.53
KDM4E B2RXH2 1/20 0.53
ALDH1A1 P00352 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
HSD17B10 Q99714 1/20 0.53
TGM2 P21980 4/20 0.53
SLC1A3 P43003 1/20 0.45
SLC1A2 P43004 1/20 0.45
SLC1A1 P43005 1/20 0.45
GBA1 P04062 1/20 0.44
HDAC1 Q13547 1/20 0.44
PRKD3 O94806 1/20 0.44
PRKCG P05129 1/20 0.44
PRKCB P05771 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19460686 0.84 TGM2 (0.39) NPY5RSCN1ASCN2ASCN3ACYP3A4
SCHEMBL17423934 0.82 TGM2 (0.62) TGM2GBA1HDAC1
SCHEMBL29543549 0.82 TGM2 (0.62) TGM2GBA1HDAC1
SCHEMBL29141911 0.81 NPY5R (0.56) NPY5RSCN1ASCN2ASCN3ACYP3A4
SCHEMBL394914 0.81 NPY5R (0.53) NPY5RSCN1ASCN2ASCN3ACYP3A4
SCHEMBL9568512 0.80 SCN1A (0.51) NPY5RSCN1ASCN2ASCN3ACYP3A4
SCHEMBL397690 0.78 TSHR (0.58) ALDH1A1TGM2HDAC1TSHRF2
SCHEMBL9568647 0.77 USP2 (0.56) KDM4EALDH1A1TGM2TSHRLMNA
SCHEMBL17423935 0.77 TGM2 (0.44) TGM2
SCHEMBL607518 0.77 CYP3A4 (0.64) NPY5RSCN1ASCN2ASCN3ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed