SCHEMBL397690

SCHEMBL397690

C=CC(=O)NCc1ccc(NS(=O)(=O)c2cccc3ccccc23)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.58
HDAC1 Q13547 3/20 0.58
PGR P06401 1/20 0.52
RORA P35398 1/20 0.51
RORC P51449 1/20 0.51
NR1H2 P55055 1/20 0.51
NR1H4 Q96RI1 1/20 0.51
ALDH1A1 P00352 1/20 0.50
HTT P42858 1/20 0.50
PFKFB3 Q16875 1/20 0.50
TGM2 P21980 2/20 0.49
SLC16A3 O15427 1/20 0.46
HCRTR1 O43613 1/20 0.45
BRD4 O60885 1/20 0.44
GHSR Q92847 1/20 0.44
TYMS P04818 1/20 0.44
F2 P00734 1/20 0.43
PRSS1 P07477 1/20 0.43
PRSS2 P07478 1/20 0.43
PRSS3 P35030 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568728 0.85 TSHR (0.64) TSHRHDAC1PGRRORARORC
SCHEMBL397470 0.81 ALDH1A1 (0.56) HDAC1ALDH1A1TGM2GHSR
SCHEMBL398955 0.80 HDAC1 (0.57) HDAC1PGRALDH1A1TGM2
SCHEMBL396618 0.79 ALDH1A1 (0.56) HDAC1ALDH1A1TGM2GHSR
SCHEMBL396803 0.79 RECQL (0.57) ALDH1A1HTTTGM2
SCHEMBL9568737 0.78 PGR (0.64) TSHRHDAC1PGRRORARORC
SCHEMBL397718 0.78 LMNA (0.56) HDAC1PGRALDH1A1TGM2
SCHEMBL398490 0.78 SLC16A3 (0.47) ALDH1A1HTTTGM2SLC16A3
SCHEMBL9568836 0.78 NPY5R (0.54) TSHRHDAC1ALDH1A1TGM2F2
SCHEMBL397222 0.76 TGM2 (0.44) TSHRHDAC1ALDH1A1HTTTGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5141838-A Lithography printing plates FUJI PHOTO FILM CO., LTD. (JP) 1992-08-25 US claimed
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
EP-1972440-B1 Negative lithographic printing plate precursor and lithographic printing method using the same FUJIFILM CORP (JP) 2010-06-23 EP disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-2105298-A1 Negative-working lithographic printing plate precursor and method of lithographic printing using same Fujifilm Corporation (JP) 2009-09-30 EP disclosed
US-20080233516-A1 NEGATIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-09-25 US disclosed
EP-1972440-A2 Negative lithographic printing plate precursor and lithographic printing method using the same FUJIFILM Corporation (JP) 2008-09-24 EP disclosed
EP-0671660-B1 Lead-frame forming material FUJI PHOTO FILM CO LTD (JP) 2001-10-17 EP disclosed
EP-1077392-A1 Photosensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2001-02-21 EP disclosed
US-5670293-A LIGHT SENSITIVE MATERIAL WITH COPPER OR NICKEL ALLOYS, DRYING A PHOTOSENSITIVE LAYER AND WINDING THE COATED WEB INTO STRIPS AND STACKING FUJI PHOTO FILM CO., LTD. (JP) 1997-09-23 US disclosed
EP-0330239-B1 Photosensitive composition FUJI PHOTO FILM CO LTD (JP) 1996-05-22 EP disclosed
EP-0671660-A2 Lead-frame forming material FUJI PHOTO FILM CO., LTD. (JP) 1995-09-13 EP disclosed
US-5141838-A Lithography printing plates FUJI PHOTO FILM CO., LTD. (JP) 1992-08-25 US disclosed
EP-0330239-A2 Photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1989-08-30 EP disclosed