SCHEMBL9568868

SCHEMBL9568868

C#C[CH]c1csc(CCC)n1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.34
DRD2 P14416 1/20 0.32
HTR2A P28223 1/20 0.32
HRH1 P35367 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9381967 0.77 SLC6A3 (0.39) SLC6A3DRD2HTR2AHRH1
SCHEMBL20340998 0.74 SLC6A3 (0.35) SLC6A3DRD2HTR2AHRH1
SCHEMBL24076016 0.72 SLC6A3 (0.34) SLC6A3DRD2HTR2AHRH1
SCHEMBL9568871 0.70 SLC6A3 (0.43) SLC6A3DRD2HTR2AHRH1
SCHEMBL9258625 0.70
SCHEMBL9261802 0.68
SCHEMBL9265364 0.68 HDAC3 (0.51)
SCHEMBL9261827 0.68 SLC6A3 (0.31) SLC6A3
SCHEMBL129530 0.67
SCHEMBL129529 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1081675-A By the new pyrethroid of thiazolic alcohol derivative, its preparation method and as the purposes of agricultural chemicals ROUSSEL UCLAF (FR) 1994-02-09 CN disclosed
EP-0556123-A1 Pyrethrinoid esters of thiazolylalcohols, process for their preparation and their use as pesticides ROUSSEL UCLAF (FR) 1993-08-18 EP disclosed