SCHEMBL9568871

SCHEMBL9568871

C#CCc1csc(CCC)n1

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 3/20 0.43
DRD2 P14416 1/20 0.40
HTR2A P28223 1/20 0.40
HRH1 P35367 1/20 0.40
HDAC1 Q13547 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7009281 0.79 SLC6A3 (0.47) SLC6A3DRD2HTR2AHRH1HDAC1
SCHEMBL11926805 0.79 SLC6A3 (0.49) SLC6A3DRD2HTR2AHRH1HDAC1
SCHEMBL14206867 0.78 SLC6A3 (0.46) SLC6A3DRD2HTR2AHRH1HDAC1
SCHEMBL127291 0.76 SLC6A3 (0.47) SLC6A3DRD2HTR2AHRH1HDAC1
SCHEMBL11366303 0.76 SLC6A3 (0.47) SLC6A3DRD2HTR2AHRH1
SCHEMBL442405 0.76 SLC6A3 (0.47) SLC6A3DRD2HTR2AHRH1HDAC1
Hydrochloric Acid SCHEMBL457520 0.74 SLC6A3 (0.46) SLC6A3DRD2HTR2AHRH1HDAC1
Hydrochloric Acid SCHEMBL21879694 0.74 SLC6A3 (0.46) SLC6A3DRD2HTR2AHRH1HDAC1
Hydrochloric Acid SCHEMBL11624078 0.74 RAB9A (0.47) SLC6A3DRD2HTR2AHRH1
SCHEMBL9262094 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0556123-A1 Pyrethrinoid esters of thiazolylalcohols, process for their preparation and their use as pesticides ROUSSEL UCLAF (FR) 1993-08-18 EP disclosed