Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | CCR8 | P51685 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | CCR9 | P51686 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568979 | 0.85 | CCR1 (0.50) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL9568947 | 0.84 | CCR1 (0.49) | CCR1CCR5CCR8NOS3NOS1 | |
| SCHEMBL10333255 | 0.78 | CCR1 (0.54) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL9538681 | 0.77 | PDE10A (0.45) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL9569066 | 0.76 | CCR1 (0.51) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL9538699 | 0.75 | CCR1 (0.50) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL13985936 | 0.74 | CCR1 (0.66) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL10333632 | 0.73 | CCR1 (0.56) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL27322683 | 0.72 | CCR1 (0.63) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL27388134 | 0.72 | CCR1 (0.46) | CCR1CCR5CCR8NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1070400-A | Benzoglyoxaline | FISONS PLC (GB) | 1993-03-31 | — | — | CN | disclosed |
| EP-0526033-A1 | Benzimidazoles | FISONS plc (GB) | 1993-02-03 | — | — | EP | disclosed |