Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | CCR8 | P51685 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.43 |
| ▸ | CCR9 | P51686 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568979 | 0.85 | CCR1 (0.50) | CCR1CCR5CCR8P2RX7CCR9 | |
| SCHEMBL9568937 | 0.84 | CCR1 (0.49) | CCR1CCR5CCR8P2RX7CCR9 | |
| SCHEMBL27927335 | 0.80 | CCR1 (0.58) | CCR1CCR5CCR8P2RX7CCR9 | |
| SCHEMBL27909626 | 0.80 | CCR1 (0.61) | CCR1CCR5CCR8P2RX7CCR9 | |
| SCHEMBL10333255 | 0.78 | CCR1 (0.54) | CCR1CCR5CCR8P2RX7CCR9 | |
| SCHEMBL25714905 | 0.77 | GRM5 (0.43) | CCR1CCR5CCR8CYP1A2TSHR | |
| SCHEMBL10333299 | 0.77 | CCR1 (0.50) | CCR1CCR5CCR8P2RX7CCR9 | |
| SCHEMBL9540847 | 0.77 | PDE10A (0.45) | CCR1CCR5CCR8P2RX7NOS3 | |
| SCHEMBL9569056 | 0.76 | CCR1 (0.51) | CCR1CCR5CCR8P2RX7CCR9 | |
| SCHEMBL10333632 | 0.73 | CCR1 (0.56) | CCR1CCR5CCR8P2RX7CCR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1070400-A | Benzoglyoxaline | FISONS PLC (GB) | 1993-03-31 | — | — | CN | disclosed |
| EP-0526033-A1 | Benzimidazoles | FISONS plc (GB) | 1993-02-03 | — | — | EP | disclosed |