Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.51 |
| ▸ | CCR5 | P51681 | 1/20 | 0.51 |
| ▸ | CCR8 | P51685 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569042 | 0.84 | CCR1 (0.53) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL9569056 | 0.83 | CCR1 (0.51) | CCR1CCR5CCR8NOS3NOS1 | |
| SCHEMBL10333208 | 0.77 | CCR1 (0.58) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL9569003 | 0.76 | NOS2 (0.53) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL9568937 | 0.76 | CCR1 (0.49) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL13985936 | 0.76 | CCR1 (0.66) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL27322683 | 0.74 | CCR1 (0.63) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL27388134 | 0.74 | CCR1 (0.46) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL9569010 | 0.73 | CCR1 (0.53) | CCR1CCR5CCR8NOS3NOS1 | |
| SCHEMBL10333247 | 0.72 | CCR1 (0.59) | CCR1CCR5CCR8NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526033-A1 | Benzimidazoles | FISONS plc (GB) | 1993-02-03 | — | — | EP | disclosed |