Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.53 |
| ▸ | CCR5 | P51681 | 1/20 | 0.53 |
| ▸ | CCR8 | P51685 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569056 | 0.84 | CCR1 (0.51) | CCR1CCR5CCR8MAPK1NOS3 | |
| SCHEMBL9569066 | 0.84 | CCR1 (0.51) | CCR1CCR5CCR8MAPK1NOS3 | |
| SCHEMBL20215206 | 0.82 | CCR1 (0.56) | CCR1CCR5CCR8MAPK1NOS3 | |
| SCHEMBL7231911 | 0.82 | CCR1 (0.63) | CCR1CCR5CCR8MAPK1NOS3 | |
| SCHEMBL9542176 | 0.79 | NPC1 (0.35) | CCR1CCR5CCR8CLK4LMNA | |
| SCHEMBL10333208 | 0.78 | CCR1 (0.58) | CCR1CCR5CCR8MAPK1NOS3 | |
| SCHEMBL9569019 | 0.76 | NOS2 (0.53) | CCR1CCR5CCR8NOS3NOS1 | |
| SCHEMBL9568979 | 0.75 | CCR1 (0.50) | CCR1CCR5CCR8MAPK1NOS3 | |
| SCHEMBL10333383 | 0.74 | CCR1 (0.56) | CCR1CCR5CCR8MAPK1NOS3 | |
| SCHEMBL10333247 | 0.73 | CCR1 (0.59) | CCR1CCR5CCR8MAPK1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526033-A1 | Benzimidazoles | FISONS plc (GB) | 1993-02-03 | — | — | EP | disclosed |