Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569190 | 0.91 | TOP1 (0.33) | TOP1PPARA | |
| SCHEMBL9569188 | 0.86 | TOP1 (0.41) | TOP1KDM4EPPARALMNA | |
| SCHEMBL9560567 | 0.84 | STAT3 (0.37) | TOP1MEN1KMT2ASTAT3KDM4E | |
| SCHEMBL9510131 | 0.80 | TOP1 (0.36) | TOP1MEN1KMT2ASTAT3KDM4E | |
| SCHEMBL9569179 | 0.79 | TOP2A (0.47) | TOP1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL9512987 | 0.78 | STAT3 (0.39) | TOP1MEN1KMT2ASTAT3KDM4E | |
| SCHEMBL9560141 | 0.77 | STAT3 (0.39) | TOP1MEN1KMT2ASTAT3KDM4E | |
| SCHEMBL9569186 | 0.76 | KDM4E (0.43) | TOP1TDP1KDM4E | |
| SCHEMBL9569159 | 0.76 | STAT3 (0.41) | TOP1MEN1KMT2ASTAT3KDM4E | |
| SCHEMBL9560451 | 0.75 | STAT3 (0.36) | TOP1MEN1KMT2ASTAT3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563734-A1 | 9-fluoro-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazine carboxylic acids and esters and their use as antiviral agents | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |