Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9569157 | 0.88 | CYP11B1 (0.35) | CYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL9560481 | 0.85 | STAT3 (0.41) | STAT3MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL10762656 | 0.81 | STAT3 (0.42) | STAT3MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL9569181 | 0.79 | STAT3 (0.38) | STAT3MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL9560653 | 0.79 | STAT3 (0.40) | STAT3MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL9569144 | 0.77 | STAT3 (0.40) | STAT3MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL9569165 | 0.76 | STAT3 (0.38) | STAT3MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL9560449 | 0.74 | TOP1 (0.39) | STAT3KDM4EHSD17B10ALDH1A1CNR1 | |
| SCHEMBL9560614 | 0.73 | STAT3 (0.42) | STAT3MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL14668818 | 0.73 | STAT3 (0.55) | STAT3KMT2AKDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563734-A1 | 9-fluoro-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazine carboxylic acids and esters and their use as antiviral agents | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |