Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.40 |
| ▸ | TOP1 | P11387 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.31 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.31 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.31 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569181 | 0.91 | STAT3 (0.38) | STAT3TOP1MAPTCNR1CNR2 | |
| SCHEMBL9569164 | 0.89 | STAT3 (0.41) | STAT3TOP1MAPT | |
| SCHEMBL9560481 | 0.86 | STAT3 (0.41) | STAT3TOP1MAPTCNR1CNR2 | |
| SCHEMBL9569160 | 0.85 | TOP1 (0.48) | STAT3TOP1KDM4E | |
| SCHEMBL10762656 | 0.82 | STAT3 (0.42) | STAT3TOP1MAPTCNR1CNR2 | |
| SCHEMBL9569173 | 0.79 | STAT3 (0.39) | STAT3TOP1MAPT | |
| SCHEMBL9560653 | 0.79 | STAT3 (0.40) | STAT3TOP1MAPTCNR1CNR2 | |
| SCHEMBL9569146 | 0.77 | CYP19A1 (0.35) | STAT3CNR1CNR2HSD17B10MEN1 | |
| SCHEMBL9569165 | 0.77 | STAT3 (0.38) | STAT3TOP1MAPTCNR1CNR2 | |
| SCHEMBL9560449 | 0.77 | TOP1 (0.39) | STAT3TOP1CNR1CNR2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563734-A1 | 9-fluoro-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazine carboxylic acids and esters and their use as antiviral agents | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |