Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569142 | 0.86 | TOP1 (0.39) | CNR1CNR2TOP1KDM4EALDH1A1 | |
| SCHEMBL10762656 | 0.86 | STAT3 (0.42) | STAT3CNR1CNR2ADRB2TOP1 | |
| SCHEMBL9560481 | 0.84 | STAT3 (0.41) | STAT3CNR1CNR2ADRB2TOP1 | |
| SCHEMBL9560653 | 0.83 | STAT3 (0.40) | STAT3CNR1CNR2ADRB2TOP1 | |
| SCHEMBL9569148 | 0.80 | STAT3 (0.38) | STAT3CNR1CNR2ADRB2TOP1 | |
| SCHEMBL9569139 | 0.80 | TOP1 (0.51) | TOP1KDM4EALDH1A1TOP2ATOP2B | |
| SCHEMBL9569181 | 0.79 | STAT3 (0.38) | STAT3CNR1CNR2TOP1KMT2A | |
| SCHEMBL9560614 | 0.78 | STAT3 (0.42) | STAT3CNR1CNR2ADRB2TOP1 | |
| SCHEMBL9569144 | 0.77 | STAT3 (0.40) | STAT3CNR1CNR2TOP1KMT2A | |
| SCHEMBL9569146 | 0.76 | CYP19A1 (0.35) | STAT3CNR1CNR2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563734-A1 | 9-fluoro-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazine carboxylic acids and esters and their use as antiviral agents | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |