Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 17/20 | 0.63 |
| ▸ | TOP2B | Q02880 | 13/20 | 0.63 |
| ▸ | TOP1 | P11387 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569171 | 0.90 | TOP2A (0.51) | TOP2ATOP2BTOP1 | |
| SCHEMBL9569169 | 0.83 | TOP1 (0.51) | TOP2ATOP2BTOP1 | |
| SCHEMBL9513013 | 0.83 | TOP2A (0.62) | TOP2ATOP2BTOP1 | |
| SCHEMBL9088225 | 0.76 | HPGD (0.64) | TOP2ATOP2BTOP1 | |
| SCHEMBL9560547 | 0.76 | TOP2A (0.58) | TOP2ATOP2BTOP1 | |
| SCHEMBL7013056 | 0.75 | KDM4E (0.60) | TOP2ATOP2BTOP1 | |
| SCHEMBL9869882 | 0.74 | TOP2A (0.61) | TOP2ATOP2BTOP1 | |
| SCHEMBL7007104 | 0.74 | KDM4E (0.63) | TOP2ATOP2BTOP1 | |
| SCHEMBL10569978 | 0.74 | KDM4E (0.60) | TOP2ATOP2BTOP1 | |
| SCHEMBL9569177 | 0.73 | TOP2A (0.53) | TOP2ATOP2BTOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563734-A1 | 9-fluoro-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazine carboxylic acids and esters and their use as antiviral agents | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |