Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.51 |
| ▸ | TOP2A | P11388 | 15/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 13/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569160 | 0.88 | TOP1 (0.48) | TOP1TOP2ATOP2BSTAT3KDM4E | |
| SCHEMBL9569173 | 0.88 | STAT3 (0.39) | TOP1TOP2ATOP2BSTAT3 | |
| SCHEMBL9569167 | 0.83 | TOP2A (0.63) | TOP1TOP2ATOP2B | |
| SCHEMBL9569153 | 0.83 | TOP1 (0.53) | TOP1TOP2ATOP2BKDM4EALDH1A1 | |
| SCHEMBL9569181 | 0.83 | STAT3 (0.38) | TOP1TOP2ATOP2BSTAT3KDM4E | |
| SCHEMBL9388538 | 0.79 | TOP1 (0.54) | TOP1TOP2ATOP2BKDM4EALDH1A1 | |
| SCHEMBL9569164 | 0.77 | STAT3 (0.41) | TOP1TOP2ATOP2BSTAT3 | |
| SCHEMBL9569139 | 0.75 | TOP1 (0.51) | TOP1TOP2ATOP2BKDM4EALDH1A1 | |
| SCHEMBL3691781 | 0.74 | TOP1 (0.75) | TOP1TOP2ATOP2B | |
| SCHEMBL9569144 | 0.73 | STAT3 (0.40) | TOP1STAT3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563734-A1 | 9-fluoro-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazine carboxylic acids and esters and their use as antiviral agents | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |