Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL9569201

C1CC2(CC2)CN1.O=C(O)C(F)(F)F

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
L3MBTL3 Q96JM7 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
TSHR P16473 1/20 0.34
HDAC2 Q92769 1/20 0.33
NPY2R P49146 1/20 0.33
ARG1 P05089 1/20 0.33
CYP1A2 P05177 2/20 0.32
CYP2D6 P10635 1/20 0.32
IRAK4 Q9NWZ3 3/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL15752165 0.92 L3MBTL3 (0.37) L3MBTL3L3MBTL1TSHRHDAC2NPY2R
Trifluoroacetic Acid SCHEMBL30122206 0.92 TSHR (0.34) L3MBTL3L3MBTL1TSHRHDAC2NPY2R
Trifluoroacetic Acid SCHEMBL29877879 0.88 CYP1A2 (0.35) TSHRNPY2RCYP1A2CYP2D6
Trifluoroacetic Acid SCHEMBL25277778 0.87 TSHR (0.30) TSHR
Trifluoroacetic Acid SCHEMBL347581 0.87 CYP1A2 (0.41) TSHRCYP1A2CYP2D6
Trifluoroacetic Acid SCHEMBL21712920 0.85
Trifluoroacetic Acid SCHEMBL5035153 0.85 CYP1A2 (0.42) TSHRCYP1A2CYP2D6
Trifluoroacetic Acid SCHEMBL30504395 0.83 L3MBTL3 (0.35) L3MBTL3L3MBTL1TSHRARG1
Trifluoroacetic Acid SCHEMBL31094826 0.81 NPY2R (0.31) L3MBTL3L3MBTL1NPY2RCYP1A2CYP2D6
Trifluoroacetic Acid SCHEMBL31439473 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118812517-A Antitumor compounds as UPR agonists and uses thereof 南京圣和药业股份有限公司 2024-10-22 CN disclosed
CN-113292479-B Preparation method of 5-azaspiro [2.4] heptane and salt thereof 南京合巨药业有限公司 2022-07-01 CN disclosed
EP-2738156-B1 9-AMINOMETHYL SUBSTITUTED TETRACYCLINE COMPOUNDS KBP BIOSCIENCES USA INC (US) 2018-01-03 EP disclosed
US-9365499-B2 9-aminomethyl substituted tetracycline compounds KBP BIOSCIENCES CO., LTD. (CN) 2016-06-14 US disclosed
US-20140179638-A1 9-AMINOMETHYL SUBSTITUTED TETRACYCLINE COMPOUNDS KBP BIOSCIENCES CO., LTD. (CN) 2014-06-26 US disclosed
EP-2738156-A1 9-AMINOMETHYL SUBSTITUTED TETRACYCLINE COMPOUND KBP Biosciences Co., Ltd. (CN) 2014-06-04 EP disclosed
EP-0541086-A1 Antibacterial 6-fluoro-quinolones having an oxime group on the substituent in position 7 Kaken Pharmaceutical Co., Ltd. (JP) 1993-05-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140179638-A1 9-AMINOMETHYL SUBSTITUTED TETRACYCLINE COMPOUNDS TET3, TET1, PRMT9 L3MBTL3 264/4885L3MBTL1 938/4885TSHR 912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.