Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.37 |
| ▸ | DNASE1 | P24855 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.33 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569235 | 0.93 | ALDH1A1 (0.40) | ALDH1A1HSD17B10ERCC1DNASE1FEN1 | |
| SCHEMBL9569238 | 0.93 | ALDH1A1 (0.40) | ALDH1A1HSD17B10ERCC1DNASE1FEN1 | |
| SCHEMBL9569216 | 0.84 | ALDH1A1 (0.44) | ALDH1A1HSD17B10ERCC1DNASE1FEN1 | |
| SCHEMBL9569218 | 0.79 | ALDH1A1 (0.42) | ALDH1A1HSD17B10ERCC1DNASE1FEN1 | |
| SCHEMBL9569221 | 0.79 | ALDH1A1 (0.42) | ALDH1A1HSD17B10ERCC1DNASE1FEN1 | |
| SCHEMBL29576625 | 0.78 | ALDH1A1 (0.49) | ALDH1A1HSD17B10ERCC1DNASE1FEN1 | |
| SCHEMBL8615747 | 0.78 | ALDH1A1 (0.49) | ALDH1A1HSD17B10ERCC1DNASE1FEN1 | |
| SCHEMBL7291426 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HSD17B10ERCC1DNASE1FEN1 | |
| SCHEMBL28826859 | 0.76 | PIK3CD (0.53) | ALDH1A1HSD17B10ERCC1DNASE1FEN1 | |
| SCHEMBL29576228 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HSD17B10ERCC1DNASE1FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541086-A1 | Antibacterial 6-fluoro-quinolones having an oxime group on the substituent in position 7 | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-05-12 | — | — | EP | disclosed |