Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569286 | 0.81 | KMT2A (0.43) | KEAP1TP53TSHRMAPK1HPGD | |
| SCHEMBL29822323 | 0.74 | TP53 (0.69) | KEAP1TP53TSHRMAPK1HPGD | |
| SCHEMBL610480 | 0.74 | TP53 (0.69) | KEAP1TP53TSHRMAPK1HPGD | |
| SCHEMBL943660 | 0.74 | KEAP1 (0.57) | KEAP1TP53TSHRMAPK1HPGD | |
| SCHEMBL7504711 | 0.73 | HPGD (0.45) | KEAP1TSHRHPGDALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL3622868 | 0.72 | KEAP1 (0.41) | KEAP1TP53TSHRMAPK1HPGD | |
| SCHEMBL9569306 | 0.72 | KDM4E (0.42) | KEAP1TSHRHPGDALDH1A1MAPT | |
| SCHEMBL27608734 | 0.70 | TP53 (0.53) | KEAP1TP53TSHRMAPK1HPGD | |
| SCHEMBL9359025 | 0.69 | KEAP1 (0.48) | KEAP1TP53TSHRMAPK1HPGD | |
| SCHEMBL8778092 | 0.69 | MEN1 (0.56) | HPGDALDH1A1MAPTHSP90AA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532058-A1 | Process for preparing halogenosulfonyl-substituted pyridine compounds | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-5128474-A | Herbicides | ISHIHARA SANGYO KAISHA LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0298752-A2 | Mercapto-substituted pyridine compounds and process for preparing the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1989-01-11 | — | — | EP | disclosed |