SCHEMBL9569309

SCHEMBL9569309

NC(=O)c1cccnc1S(=O)(=O)Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.50
RAB9A P51151 3/20 0.45
SMN1; SMN2 Q16637 4/20 0.44
KDM4E B2RXH2 6/20 0.43
ALDH1A1 P00352 5/20 0.43
HPGD P15428 4/20 0.43
HSD17B10 Q99714 3/20 0.43
MAPT P10636 4/20 0.42
NPC1 O15118 1/20 0.42
AHR P35869 1/20 0.42
LMNA P02545 2/20 0.42
NAPRT Q6XQN6 1/20 0.42
P2RX7 Q99572 1/20 0.41
HTT P42858 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
TSHR P16473 2/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
BLM P54132 1/20 0.39
AGER Q15109 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2213767 0.84 PARP1 (0.51) PARP1RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL27740430 0.84 PARP1 (0.51) PARP1RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL9826240 0.84 LMNA (0.56) RAB9ASMN1; SMN2KDM4EALDH1A1MAPT
SCHEMBL9953506 0.82 PARP1 (0.50) PARP1RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL31368390 0.78 PARP1 (0.46) PARP1RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL3714382 0.78 TDP1 (0.50) KDM4EALDH1A1HSD17B10LMNAP2RX7
SCHEMBL30151488 0.78 SMN1; SMN2 (0.40) SMN1; SMN2KDM4EALDH1A1MAPTLMNA
SCHEMBL9244018 0.78 SMN1; SMN2 (0.40) SMN1; SMN2KDM4EALDH1A1MAPTLMNA
SCHEMBL9955204 0.77 PARP1 (0.45) PARP1RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL27996476 0.76 KDM4E (0.48) PARP1RAB9ASMN1; SMN2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-212032035-U Oxychlorination control device for nicosulfuron production 安徽工业大学 2020-11-27 CN disclosed
CN-212032035-U Oxychlorination control device for nicosulfuron production 安徽工业大学 2020-11-27 CN disclosed
CN-111974329-A Control method for oxychlorination reaction in nicosulfuron production 马鞍山安鸿生物科技有限责任公司 2020-11-24 CN disclosed
EP-0532058-A1 Process for preparing halogenosulfonyl-substituted pyridine compounds ISHIHARA SANGYO KAISHA, LTD. (JP) 1993-03-17 EP disclosed
EP-0298752-A2 Mercapto-substituted pyridine compounds and process for preparing the same ISHIHARA SANGYO KAISHA, LTD. (JP) 1989-01-11 EP disclosed