Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5151972 | 0.85 | NAPRT (0.56) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL27740430 | 0.85 | PARP1 (0.51) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9569309 | 0.84 | PARP1 (0.50) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9953506 | 0.84 | PARP1 (0.50) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8629880 | 0.80 | CA1 (0.57) | KDM4EALDH1A1HSD17B10TSHRP2RX7 | |
| SCHEMBL2705046 | 0.80 | P2RX7 (0.41) | PARP1KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL9363595 | 0.80 | P2RX7 (0.49) | NAPRTP2RX7LMNACA1CA2 | |
| SCHEMBL31368390 | 0.80 | PARP1 (0.46) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9955204 | 0.78 | PARP1 (0.45) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27996476 | 0.77 | KDM4E (0.48) | PARP1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110035657-A | Liquid herbicidal composition containing sulfonylurea and Li salt | 巴特尔英国有限公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-107427010-A | LIQUID SULFONYLUREA-CONTAINING HERBICIDAL COMPOSITIONS | 三井农业化学国际有限公司 | 2017-12-01 | — | — | CN | disclosed |
| EP-2342175-B1 | NITRIC OXIDE RELEASING AMINO ACID ESTER COMPOUND, COMPOSITION AND METHOD OF USE | NITROGENIX INC (VG) | 2015-05-27 | — | — | EP | disclosed |
| EP-2342175-A1 | NITRIC OXIDE RELEASING AMINO ACID ESTER COMPOUND, COMPOSITION AND METHOD OF USE | Nitrogenix Inc. (VG) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010034118-A1 | NITRIC OXIDE RELEASING AMINO ACID ESTER COMPOUND, COMPOSITION AND METHOD OF USE | ORAL DELIVERY TECHNOLOGY LTD. (CA) | 2010-04-01 | — | — | WO | disclosed |
| US-20070010571-A1 | Nitrosated and nitrosylated cardiovascular compounds, compositions and methods of use | NITROMED, INC. (US) | 2007-01-11 | — | — | US | disclosed |
| US-4776878-A | PLANT GROWTH REGULATORS OR HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-10-11 | — | — | US | disclosed |
| US-4544401-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-10-01 | — | — | US | disclosed |
| US-4522645-A | PRE AND POST EMERGENCE HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-06-11 | — | — | US | disclosed |
| US-4435206-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-03-06 | — | — | US | disclosed |
| EP-0013480-B1 | HERBICIDAL PYRIDINESULFONAMIDES, PREPARATION AND USE THEREOF AND COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-03-16 | — | — | EP | disclosed |
| EP-0013480-A2 | Herbicidal pyridinesulfonamides, preparation and use thereof and compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-07-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010571-A1 | Nitrosated and nitrosylated cardiovascular compounds, compositions and methods of use | REN, ACE, AGTR1 | PARP1 1998/4885KDM4E 2770/4885ALDH1A1 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.