Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569356 | 0.84 | CACNA1C (0.39) | CACNA1CDRD4TP53MAPTTHRB | |
| SCHEMBL11011280 | 0.80 | CACNA1C (0.35) | CACNA1CDRD4BCHE | |
| SCHEMBL30085708 | 0.78 | HRH3 (0.37) | MEN1POLBKMT2ACHRM2CHRM4 | |
| SCHEMBL9569380 | 0.74 | GSK3B (0.34) | MEN1KMT2ACACNA1CBCHE | |
| SCHEMBL30085710 | 0.74 | POLB (0.39) | MEN1POLBKMT2ACHRM2CHRM4 | |
| SCHEMBL9569373 | 0.73 | GSK3B (0.36) | MEN1KMT2ASMN1; SMN2TP53MAPT | |
| SCHEMBL11012110 | 0.73 | GSK3B (0.36) | CACNA1CBCHE | |
| SCHEMBL11005893 | 0.72 | GSK3B (0.34) | CACNA1CBCHE | |
| SCHEMBL11008993 | 0.71 | GSK3B (0.34) | CACNA1CBCHE | |
| SCHEMBL11008882 | 0.71 | GSK3B (0.34) | CACNA1CBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524055-A1 | Imidazo(2,1-b)benzothiazole-3-acetamide derivatives, process for their preparation and their therapeutical use | SYNTHELABO (FR) | 1993-01-20 | — | — | EP | disclosed |