Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569380 | 0.91 | GSK3B (0.34) | CACNA1CGSK3BBCHELMNAPPARG | |
| SCHEMBL9569373 | 0.89 | GSK3B (0.36) | GSK3BBCHELMNAMAPTTP53 | |
| SCHEMBL11011280 | 0.84 | CACNA1C (0.35) | CACNA1CGSK3BBCHELMNAHPGD | |
| SCHEMBL9569385 | 0.84 | MEN1 (0.44) | CACNA1CBCHEDRD4MAPTTP53 | |
| SCHEMBL9569336 | 0.81 | BACE1 (0.36) | BCHEHPGDMAPTTP53KDM4E | |
| SCHEMBL11005893 | 0.79 | GSK3B (0.34) | CACNA1CGSK3BBCHELMNAHPGD | |
| SCHEMBL11008993 | 0.78 | GSK3B (0.34) | CACNA1CGSK3BBCHELMNAHPGD | |
| SCHEMBL9259658 | 0.78 | SIGMAR1 (0.31) | LMNA | |
| SCHEMBL11008882 | 0.75 | GSK3B (0.34) | CACNA1CGSK3BBCHELMNAHPGD | |
| SCHEMBL11011669 | 0.75 | GSK3B (0.34) | CACNA1CGSK3BBCHELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524055-A1 | Imidazo(2,1-b)benzothiazole-3-acetamide derivatives, process for their preparation and their therapeutical use | SYNTHELABO (FR) | 1993-01-20 | — | — | EP | disclosed |