Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569356 | 0.91 | CACNA1C (0.39) | GSK3BBCHEPPARGCACNA1CLMNA | |
| SCHEMBL9569373 | 0.91 | GSK3B (0.36) | GSK3BBCHEACHEPPARGKMT2A | |
| SCHEMBL9569336 | 0.88 | BACE1 (0.36) | BCHEKMT2AMEN1 | |
| SCHEMBL9259658 | 0.82 | SIGMAR1 (0.31) | SIGMAR1LMNA | |
| SCHEMBL9569405 | 0.80 | EGFR (0.43) | BCHEKMT2AMEN1 | |
| SCHEMBL9569385 | 0.74 | MEN1 (0.44) | BCHEKMT2ACACNA1CMEN1 | |
| SCHEMBL11011280 | 0.73 | CACNA1C (0.35) | GSK3BBCHEPPARGCACNA1CLMNA | |
| SCHEMBL9271818 | 0.73 | PRNP (0.31) | GSK3BBCHEKMT2AMEN1LMNA | |
| SCHEMBL11004064 | 0.73 | MAOA (0.38) | GSK3BBCHEKMT2AMEN1LMNA | |
| SCHEMBL30085745 | 0.72 | BRD4 (0.41) | GSK3BPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524055-A1 | Imidazo(2,1-b)benzothiazole-3-acetamide derivatives, process for their preparation and their therapeutical use | SYNTHELABO (FR) | 1993-01-20 | — | — | EP | disclosed |