Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10714727 | 0.76 | CALM1 (0.42) | CALM1MEN1ELANEKMT2AAOC3 | |
| SCHEMBL28324839 | 0.72 | CALM1 (0.42) | CALM1AOC3SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL2479409 | 0.62 | CALM1 (0.44) | CALM1MEN1ELANEKMT2ASMN1; SMN2 | |
| SCHEMBL6504361 | 0.60 | CALM1 (0.42) | CALM1MEN1ELANEKMT2AAOC3 | |
| Diphenylmethane SCHEMBL28172316 | 0.60 | CALM1 (1.00) | CALM1ALDH1A1PLA2G10PLA2G2ALMNA | |
| Diphenylmethane SCHEMBL3792579 | 0.60 | CALM1 (1.00) | CALM1ALDH1A1PLA2G10PLA2G2ALMNA | |
| Diphenylmethane SCHEMBL14763944 | 0.60 | CALM1 (1.00) | CALM1ALDH1A1PLA2G10PLA2G2ALMNA | |
| Diphenylmethane SCHEMBL1303 | 0.60 | CALM1 (1.00) | CALM1ALDH1A1PLA2G10PLA2G2ALMNA | |
| Diphenylmethane SCHEMBL4361124 | 0.60 | CALM1 (1.00) | CALM1ALDH1A1PLA2G10PLA2G2ALMNA | |
| SCHEMBL5602992 | 0.59 | CALM1 (0.46) | CALM1SMN1; SMN2ALDH1A1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562261-A2 | Sulphonylbenzyl substituted imidazoles | BAYER AG (DE) | 1993-09-29 | — | — | EP | disclosed |