Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 10/20 | 0.52 |
| ▸ | PNP | P00491 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | PAH | P00439 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569464 | 0.86 | HPRT1 (0.58) | HPRT1PNPUSP2CASP7HSD17B10 | |
| SCHEMBL9569467 | 0.81 | HPRT1 (0.52) | HPRT1 | |
| SCHEMBL9569709 | 0.76 | HPRT1 (0.59) | HPRT1PNPUSP2CASP7HSD17B10 | |
| SCHEMBL9569639 | 0.75 | HPRT1 (0.56) | HPRT1PNP | |
| SCHEMBL711245 | 0.74 | HPRT1 (0.55) | HPRT1USP2CASP7HSD17B10NOS1 | |
| SCHEMBL571080 | 0.74 | HPRT1 (0.60) | HPRT1USP2CASP7HSD17B10NOS1 | |
| SCHEMBL9569460 | 0.74 | PNP (0.56) | HPRT1PNP | |
| SCHEMBL9569463 | 0.74 | PNP (0.56) | HPRT1PNP | |
| Phosphoric Acid SCHEMBL1664405 | 0.73 | HPRT1 (0.62) | HPRT1PNP | |
| SCHEMBL5256049 | 0.73 | HPRT1 (0.56) | HPRT1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532423-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | disclosed |