Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 4/20 | 0.51 |
| ▸ | TYMP | P19971 | 3/20 | 0.46 |
| ▸ | TK2 | O00142 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569522 | 1.00 | TK1 (0.51) | TK1TYMPTK2MAPK1HPGD | |
| SCHEMBL9569431 | 0.93 | TYMP (0.48) | TK1TYMPTK2MAPK1HPGD | |
| SCHEMBL9569426 | 0.93 | TYMP (0.48) | TK1TYMPTK2MAPK1HPGD | |
| SCHEMBL9569744 | 0.84 | TYMP (0.55) | TK1TYMPTK2MAPK1HPGD | |
| SCHEMBL9569742 | 0.84 | TYMP (0.55) | TK1TYMPTK2MAPK1HPGD | |
| SCHEMBL9569560 | 0.81 | TK1 (0.45) | TK1TYMPTK2MAPK1HPGD | |
| SCHEMBL9569542 | 0.81 | TK1 (0.45) | TK1TYMPTK2MAPK1HPGD | |
| SCHEMBL9569580 | 0.80 | TK1 (0.39) | TK1TYMPMAPK1HPGD | |
| SCHEMBL9569569 | 0.80 | TK1 (0.39) | TK1TYMPMAPK1HPGD | |
| SCHEMBL9569563 | 0.78 | TYMP (0.46) | TK1TYMPTK2MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532423-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | disclosed |