Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 9/20 | 0.45 |
| ▸ | TYMP | P19971 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TK2 | O00142 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569542 | 1.00 | TK1 (0.45) | TK1TYMPMAPK1HPGDTK2 | |
| SCHEMBL9569664 | 0.84 | TYMP (0.52) | TK1TYMPMAPK1HPGDTK2 | |
| SCHEMBL9569651 | 0.84 | TYMP (0.52) | TK1TYMPMAPK1HPGDTK2 | |
| SCHEMBL9569426 | 0.82 | TYMP (0.48) | TK1TYMPMAPK1HPGDTK2 | |
| SCHEMBL9569431 | 0.82 | TYMP (0.48) | TK1TYMPMAPK1HPGDTK2 | |
| SCHEMBL9569509 | 0.81 | TK1 (0.51) | TK1TYMPMAPK1HPGDTK2 | |
| SCHEMBL9569522 | 0.81 | TK1 (0.51) | TK1TYMPMAPK1HPGDTK2 | |
| SCHEMBL7219926 | 0.77 | MAPK1 (0.54) | TK1TYMPMAPK1HPGDTK2 | |
| SCHEMBL9569715 | 0.76 | TYMP (0.47) | TK1TYMPMAPK1HPGD | |
| SCHEMBL9569711 | 0.76 | TYMP (0.47) | TK1TYMPMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532423-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | disclosed |