Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569469 | 0.77 | FGFR1 (0.38) | EP300 | |
| SCHEMBL9569479 | 0.77 | FGFR1 (0.38) | EP300 | |
| SCHEMBL9569496 | 0.68 | ENPP1 (0.53) | — | |
| SCHEMBL9569474 | 0.68 | ENPP1 (0.53) | — | |
| SCHEMBL9569542 | 0.68 | TK1 (0.45) | HPGD | |
| SCHEMBL9569560 | 0.68 | TK1 (0.45) | HPGD | |
| SCHEMBL9569510 | 0.65 | FGFR1 (0.40) | EP300 | |
| SCHEMBL9569501 | 0.65 | FGFR1 (0.40) | EP300 | |
| SCHEMBL9569726 | 0.62 | FGFR1 (0.46) | EP300 | |
| SCHEMBL9569738 | 0.62 | FGFR1 (0.46) | EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532423-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | disclosed |