Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | FYN | P06241 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742937 | 0.84 | TTR (0.50) | TTRCNR2NPC1RAB9AALDH1A1 | |
| SCHEMBL9742941 | 0.84 | TTR (0.50) | TTRCNR2NPC1RAB9AALDH1A1 | |
| SCHEMBL31507116 | 0.77 | MAOB (0.41) | MAOBTTRPTK6MEN1KMT2A | |
| SCHEMBL9875977 | 0.77 | IAPP (0.40) | TTRCNR2RAB9AALDH1A1TDP1 | |
| SCHEMBL9281951 | 0.77 | IAPP (0.40) | TTRCNR2RAB9AALDH1A1TDP1 | |
| SCHEMBL10765760 | 0.77 | TRPA1 (0.48) | TTRCNR2MEN1KMT2AALDH1A1 | |
| SCHEMBL10767153 | 0.77 | TRPA1 (0.48) | TTRCNR2MEN1KMT2AALDH1A1 | |
| SCHEMBL31732969 | 0.75 | KMT2A (0.41) | MAOBMEN1KMT2AHSP90AA1ALDH1A1 | |
| SCHEMBL31071896 | 0.75 | MAOB (0.58) | MAOBTTRPTK6MEN1KMT2A | |
| SCHEMBL21224294 | 0.75 | MAOB (0.58) | MAOBTTRPTK6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560554-A2 | Antitumor compositions and methods of treatment | ELI LILLY AND COMPANY (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5169860-A | Benzofuran or benzothiophene arylsulfonylureas | ELI LILLY AND COMPANY (US) | 1992-12-08 | — | — | US | disclosed |