Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 11/20 | 0.40 |
| ▸ | CA1 | P00915 | 9/20 | 0.40 |
| ▸ | CA2 | P00918 | 9/20 | 0.40 |
| ▸ | CA7 | P43166 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 7/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569782 | 0.78 | CA12 (0.47) | CA9CA1CA2CA7MEN1 | |
| SCHEMBL9569781 | 0.78 | CNR1 (0.48) | CA9CA1CA2MEN1KMT2A | |
| SCHEMBL9569778 | 0.78 | CNR1 (0.59) | CA9CA1CA2CA7MEN1 | |
| SCHEMBL9569777 | 0.78 | CA12 (0.57) | CA9CA1CA2CA7MEN1 | |
| Water SCHEMBL9569771 | 0.77 | CNR1 (0.58) | CA9CA1CA2CA7MEN1 | |
| SCHEMBL9476568 | 0.75 | CA1 (0.40) | CA9CA1CA2CA7MEN1 | |
| SCHEMBL9479492 | 0.75 | CA1 (0.40) | CA9CA1CA2CA7MEN1 | |
| SCHEMBL11539598 | 0.69 | CNR1 (0.54) | KMT2ACNR1TP53CTNNB1WNT3A | |
| SCHEMBL9422413 | 0.69 | CA12 (0.50) | CA9CA1CA2CA7MEN1 | |
| SCHEMBL9524746 | 0.68 | CA2 (0.53) | CA9CA1CA2CA7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560554-A2 | Antitumor compositions and methods of treatment | ELI LILLY AND COMPANY (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5169860-A | Benzofuran or benzothiophene arylsulfonylureas | ELI LILLY AND COMPANY (US) | 1992-12-08 | — | — | US | disclosed |