Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 3/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2268683 | 0.85 | LMNA (0.51) | MEN1KMT2AFGFR1SRCHDAC6 | |
| SCHEMBL9598443 | 0.84 | MEN1 (0.49) | MEN1KMT2AFGFR1SRCHDAC6 | |
| SCHEMBL9038653 | 0.83 | LMNA (0.49) | MEN1KMT2AFGFR1SRCHDAC6 | |
| SCHEMBL2273596 | 0.81 | FGFR1 (0.51) | MEN1KMT2AFGFR1SRCHDAC6 | |
| SCHEMBL21591501 | 0.81 | LMNA (0.48) | MEN1KMT2AFGFR1SRCHDAC6 | |
| SCHEMBL110815 | 0.77 | FGFR1 (0.48) | MEN1KMT2AFGFR1SRCHDAC6 | |
| SCHEMBL2270840 | 0.75 | FGFR1 (0.56) | MEN1KMT2AFGFR1SRCHDAC6 | |
| SCHEMBL113563 | 0.74 | FGFR1 (0.44) | MEN1KMT2AFGFR1SRCHDAC6 | |
| SCHEMBL12478700 | 0.74 | HCRTR2 (0.47) | MEN1KMT2AFGFR1SRCHDAC6 | |
| SCHEMBL9570452 | 0.73 | TNF (0.47) | MEN1KMT2AMTNR1AMTNR1BTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | disclosed |
| EP-0555825-A1 | Imidazo(1,2-a)pyridines as angiotensin-II-antagonists | Dr. Karl Thomae GmbH (DE) | 1993-08-18 | — | — | EP | disclosed |